靶向性病毒载体（targeted viral vector）：是指能特异性地结合并感染某种细胞的病毒载体 。靶向性病毒载体的产生主要有两种方法 。一种方法是将病毒颗粒与某一靶向分子（Harari OA et al.1999 ）或特异性抗体（Bartlett JS et al. 1999）偶联；另一种方法是通过改变病毒外壳蛋白的结构，使其对细胞的亲嗜性发生改变（Reynolds P et al. 1999；Krasnykh VN et al. 1996 ） 。
参考文献
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